Had chronic nephritis can be much longer this disease can be cured? Chronic nephritis, short for chronic glomerulonephritis, can be transformed from acute nephritis, the disease is quite stubborn, clinically complete cure is considerably more difficult. Some patients with chronic nephritis it very serious thought to be life threatening, there would be a "chronic nephritis can be much longer" questions, in fact, chronic nephritis that you did not think that serious, as long as the development of renal failure , uremia, is not life-threatening, so worry much longer is not necessary. In the case of patients with chronic nephritis, should ask is "chronic nephritis can be cured?" What methods can solve the problem of no recurrence!
What can cure chronic nephritis, even to the radical no recurrence of the purpose? The treatment of chronic nephritis is a gradual process, need to be persistent, and all those responsible for hospitals, doctors and patients should follow the objective law, not engage in the "Great Leap Forward" in the course of the treatment of chronic nephritis.
Lead to either chronic nephritis or other kidney disease, the reason is that of progression of kidney fibrosis injury, destruction of renal cell structure damage of the glomerular cell function. The cell structure was fibrosis of damage and failure is the root cause of various types of kidney disease, "this", due to functional damage caused by proteinuria, serum creatinine increased "standard".
Micro-based medicine to penetrate the treatment of chronic nephritis different from the other in order to reduce urinary protein excretion, lower creatinine of the "standard" the next big effort, but the micro-through from the start the factors leading to renal fibrosis - kidney disorders, ischemic , hypoxic began.
Treatment of chronic nephritis need treatment for impaired renal intrinsic cells from the fundamental blocking renal fibrosis process, fundamentally, the infiltration therapy of micro-based traditional Chinese medicine mainly play the following role to get treatment!Specific description is as follows:
1.Vasodilators: of micro-penetration therapy of Chinese medicine through effective Chinese medicines dilate blood vessels, effectively improve renal ischemia and hypoxia, and to provide more oxygen and blood for the kidneys, so as to better accelerate the repair of renal intrinsic cells.
2.micro therapy for the penetration of traditional Chinese medicine through the anti-inflammatory, anticoagulant to inactivate inflammatory factors, and virulence factors of renal fibrosis process, and to prevent blood clots, blood clotting occurs, further blocking renal fibrosis, and repair damaged of renal intrinsic cells.
3.Also note that for the treatment of chronic nephritis immunosorbent assay, clear the immune complexes of patients' bodies to provide a secure and stable environment within the patients with late repair.
Through the rational application of the above treatment, the mesangial cells of the glomerular capillary repair, will be natural recovery of its normal physiological function.Mesangial cells of the barrier function will receive a reply, after the recovery of these functions, protein and other clinical symptoms also vanish. Effective treatment of chronic nephritis, to achieve true "cure disease before treatment, the disease is cured cases from extinction, so as to effectively prevent relapse.
Learn more knowledge of kidney disease, early found early treatment, prevention of dialysis, improve the quality of life. http://www.nephritiscn.com
Showing posts with label Treatment. Show all posts
Showing posts with label Treatment. Show all posts
Thursday, April 19, 2012
Friday, April 13, 2012
How to control the hypertension of patients with chronic nephritis?
Chronic nephritis, the residual and (or) had lesions of the renal unit in
compensatory hemodynamic status, systemic hypertension will undoubtedly add to
this condition, leading to glomerular injury, and therefore patients with
chronic nephritis should be actively controlled high blood pressure, prevent
deterioration of renal function.
In recent years, through a series of studies confirmed that most scholars have angiotensin converting enzyme inhibitors as first-line antihypertensive drugs. Lately, a lot of clinical studies confirmed that calcium antagonists such as nifedipine, nicardipine equal treatment of hypertension and renal function deterioration is more positive effect.That calcium antagonists, despite the slight expansion of the role of afferent arterioles, but it has significantly reduced the role of systemic blood pressure, so make the uninvolved or only partially involved glomerular hemodynamics, the high metabolic statusbe improved; In addition, calcium channel blockers reduce oxygen consumption, inhibition of platelet aggregation through the membrane effect of reducing the excessive oxidation of the calcium in the interstitial deposition and reduce the cell membrane, so as to achieve to reduce kidney damage and stable renal function. Clinical reports, short-term (4 weeks) or long (1-2 years) with calcium antagonist treatment of nephritis in patients with chronic renal insufficiency has not revealed any glomerular injury, but clearly demonstrated that it is angiotensin converting enzyme inhibitors is very similar to the efficacy of renal function deterioration. And angiotensin converting enzyme inhibitors at lowering urinary protein role for it in general. It should be noted that some scholars believe that the calcium antagonists impact on renal function is still a need for more long-term observation.
β-blockers, such as the United States and more peace of mind, Atenolol, has a good effect on the renin-dependent hypertension. beta-blockers reduce renin, although the drug reduce cardiac output, but does not affect renal blood flow and GFR, it is also used for the treatment of renal hypertension. It should be noted that some beta-blockers such as atenolol and naphthalene hydroxyl peace of mind, low-fat-soluble, since renal excretion, so renal insufficiency should pay attention to adjust the dose and extending administration time.
In addition, vasodilators such as hydralazine antihypertensive effect, it can be combined with beta-blockers reduce vasodilators stimulate renin angiotensin system side effects (such as rapid heartbeat, water and sodium retention ), and may improve the therapeutic effect. Hydralazine general daily 200mg, but must be alert to the possibility of drug-induced lupus erythematosus-like syndrome.
Edema renal, can add to a thiazide diuretic; poor renal function (serum creatinine> 200μmol / L), thiophene triazine efficacy or invalid, it should use loop diuretics marrow .Chronic nephritis patients treated with diuretics should be noted that the electrolyte imbalance in the body, and to pay attention to the tendency to aggravate hyperlipidemia, hypercoagulable state.
In recent years, through a series of studies confirmed that most scholars have angiotensin converting enzyme inhibitors as first-line antihypertensive drugs. Lately, a lot of clinical studies confirmed that calcium antagonists such as nifedipine, nicardipine equal treatment of hypertension and renal function deterioration is more positive effect.That calcium antagonists, despite the slight expansion of the role of afferent arterioles, but it has significantly reduced the role of systemic blood pressure, so make the uninvolved or only partially involved glomerular hemodynamics, the high metabolic statusbe improved; In addition, calcium channel blockers reduce oxygen consumption, inhibition of platelet aggregation through the membrane effect of reducing the excessive oxidation of the calcium in the interstitial deposition and reduce the cell membrane, so as to achieve to reduce kidney damage and stable renal function. Clinical reports, short-term (4 weeks) or long (1-2 years) with calcium antagonist treatment of nephritis in patients with chronic renal insufficiency has not revealed any glomerular injury, but clearly demonstrated that it is angiotensin converting enzyme inhibitors is very similar to the efficacy of renal function deterioration. And angiotensin converting enzyme inhibitors at lowering urinary protein role for it in general. It should be noted that some scholars believe that the calcium antagonists impact on renal function is still a need for more long-term observation.
β-blockers, such as the United States and more peace of mind, Atenolol, has a good effect on the renin-dependent hypertension. beta-blockers reduce renin, although the drug reduce cardiac output, but does not affect renal blood flow and GFR, it is also used for the treatment of renal hypertension. It should be noted that some beta-blockers such as atenolol and naphthalene hydroxyl peace of mind, low-fat-soluble, since renal excretion, so renal insufficiency should pay attention to adjust the dose and extending administration time.
In addition, vasodilators such as hydralazine antihypertensive effect, it can be combined with beta-blockers reduce vasodilators stimulate renin angiotensin system side effects (such as rapid heartbeat, water and sodium retention ), and may improve the therapeutic effect. Hydralazine general daily 200mg, but must be alert to the possibility of drug-induced lupus erythematosus-like syndrome.
Edema renal, can add to a thiazide diuretic; poor renal function (serum creatinine> 200μmol / L), thiophene triazine efficacy or invalid, it should use loop diuretics marrow .Chronic nephritis patients treated with diuretics should be noted that the electrolyte imbalance in the body, and to pay attention to the tendency to aggravate hyperlipidemia, hypercoagulable state.
Angiotensin converting enzyme inhibitors for patients with chronic nephritis What is the significance?
In recent years by a large number of animal experiments and nephritis in
patients with controlled clinical observation has been confirmed, unless there
are certainly antihypertensive efficacy of the drug can reduce glomerular
pressure, there is certainly delay the deterioration of renal function, lower
urinary protein (20% to 40%) and reduce the role of glomerular sclerosis.
Commonly used preparations the mercapto tensiomin proline acid, typical doses of
25 to 50 mg / 3 times a day, clinical; without thiol according to Na Puli, the
long duration of action, the commonly used dose of 5 to 10 mg / day 1.The drugs
to reduce the main mechanism of ball pressure, protect and stabilize the renal
function as follows:
① The expansion of glomerular artery, small arteries of the ball is more significant than the afferent artery dilation, and therefore reduce the pressure inside the ball, reducing renal ball high blood dynamics;
② The angiotensin II-stimulated proximal tubular ammonium, class preparation can reduce the angiotensin II level and (or) l hyperkalemia and reduce the production of ammonium, will help reduce the renal hypertrophy and avoid excessive ammonium generated by the alternative pathway activation of complement induced tubulointerstitial lesions.
The application of such agents should pay attention to can cause hyperkalemia (especially renal dysfunction), other side effects include rash, itching, fever, flu-like symptoms, diminished sense of taste and rare granulocytes reduce. Some people think that class preparation may cause acute drug-induced interstitial nephritis.
① The expansion of glomerular artery, small arteries of the ball is more significant than the afferent artery dilation, and therefore reduce the pressure inside the ball, reducing renal ball high blood dynamics;
② The angiotensin II-stimulated proximal tubular ammonium, class preparation can reduce the angiotensin II level and (or) l hyperkalemia and reduce the production of ammonium, will help reduce the renal hypertrophy and avoid excessive ammonium generated by the alternative pathway activation of complement induced tubulointerstitial lesions.
The application of such agents should pay attention to can cause hyperkalemia (especially renal dysfunction), other side effects include rash, itching, fever, flu-like symptoms, diminished sense of taste and rare granulocytes reduce. Some people think that class preparation may cause acute drug-induced interstitial nephritis.
Tuesday, April 10, 2012
Children with IgA nephropathy renal damage which several types?
IgA nephropathy (1gAGN) is a group associated with system disease, renal
biopsy immune pathology in glomerular mesangial granular deposition of IgA-based
disease.IgAGN for the pathological diagnosis of an immune name, clinical
glomerulonephritis with hematuria as the main manifestation, but also led to one
of the main end-stage renal failure. That the Department of an independent
clinical a pathological syndrome. Renal damage following types:
First, episodes of gross hematuria
Often in a variety of respiratory tract infections in 1-3d after gross hematuria, it is also known as pharyngitis synchronization hematuria, this common sense of acute chain glomerulonephritis. Deformability of urinary red cell morphology, suggestive of glomerular hematuria. I have seen homes in addition to gross hematuria, and in some cases accompanied by the waist and (or) severe abdominal pain, often misdiagnosed as urinary calculi, acute abdomen (appendicitis). Such abdominal pain mechanism may be associated with inflammatory lesions of small arteries in the ureter or gastrointestinal mucosa manifestations of systemic small vessel vasculitis lesions. In addition, the electron microscope shows submucosal small artery injury was fibrinoid necrosis, IgA, and C3, and fibrin deposition to support IgAGN gastrointestinal tract has also been compromised. Low back pain associated with urinary retention or temporary oliguria may be of small blood clots occur in the urinary tract caused by a temporary obstruction.
Second, the nephrotic syndrome
Individually or in some cases associated with hypertension, hematuria. If the histopathological glomerular sclerosis and renal vascular sclerosis poor prognosis.Shanghai Children's Hospital have reported 20 cases IgAGN, which manifested as nephrotic-type, 9 cases (47%), showing that this type of a certain proportion of children IgAGN.
Third, the nephritic syndrome
This type of performance with / without mild edema of asymptomatic microscopic hematuria, often misdiagnosed as the chain sense glomerulonephritis more common in urine screening examination and confirmed by biopsy.
Fourth, the simple proteinuria
Proteinuria as the first symptom in the pediatric majority showed mild or moderate proteinuria without edema and other symptoms of kidney damage.
Fifth, rapidly progressive glomerulonephritis
Rare. Continuous gross hematuria, proteinuria associated with heart, brain involvement, the abrupt deterioration of short-term renal function, renal biopsy widely (50% -100%) glomerular crescent form. Severe hematuria hemoglobin on renal tubular toxicity and tubular obstruction with acute tubular necrosis.
First, episodes of gross hematuria
Often in a variety of respiratory tract infections in 1-3d after gross hematuria, it is also known as pharyngitis synchronization hematuria, this common sense of acute chain glomerulonephritis. Deformability of urinary red cell morphology, suggestive of glomerular hematuria. I have seen homes in addition to gross hematuria, and in some cases accompanied by the waist and (or) severe abdominal pain, often misdiagnosed as urinary calculi, acute abdomen (appendicitis). Such abdominal pain mechanism may be associated with inflammatory lesions of small arteries in the ureter or gastrointestinal mucosa manifestations of systemic small vessel vasculitis lesions. In addition, the electron microscope shows submucosal small artery injury was fibrinoid necrosis, IgA, and C3, and fibrin deposition to support IgAGN gastrointestinal tract has also been compromised. Low back pain associated with urinary retention or temporary oliguria may be of small blood clots occur in the urinary tract caused by a temporary obstruction.
Second, the nephrotic syndrome
Individually or in some cases associated with hypertension, hematuria. If the histopathological glomerular sclerosis and renal vascular sclerosis poor prognosis.Shanghai Children's Hospital have reported 20 cases IgAGN, which manifested as nephrotic-type, 9 cases (47%), showing that this type of a certain proportion of children IgAGN.
Third, the nephritic syndrome
This type of performance with / without mild edema of asymptomatic microscopic hematuria, often misdiagnosed as the chain sense glomerulonephritis more common in urine screening examination and confirmed by biopsy.
Fourth, the simple proteinuria
Proteinuria as the first symptom in the pediatric majority showed mild or moderate proteinuria without edema and other symptoms of kidney damage.
Fifth, rapidly progressive glomerulonephritis
Rare. Continuous gross hematuria, proteinuria associated with heart, brain involvement, the abrupt deterioration of short-term renal function, renal biopsy widely (50% -100%) glomerular crescent form. Severe hematuria hemoglobin on renal tubular toxicity and tubular obstruction with acute tubular necrosis.
Monday, April 9, 2012
Best time of summer, chronic kidney disease treatment
Many kidney specialists pointed out that sick patients with chronic kidney
disease need to raise slowly, but in the period of recuperation, the need to
receive standard treatment, as early as day treatment for kidney protection
significance is not the same, in the summer of kidney patients to ignore is the
treatment chronic nephropathy season.
Why summer is the best season for the treatment of chronic kidney disease? Chinese medicine believes that, especially the dog days of summer, as temperatures rise, the human body yang rising, meridian accessible, with plenty of blood, the resistance is relatively high; the same time, the human body in various tissues and organs function, ability to repair itself in a year the best level. At this point, patients with chronic kidney disease often feel "good", the external symptoms of a variety of kidney disease also are relatively mild. Therefore, some patients are often in the summer of their condition "underestimate the enemy," the idea, they do not rush to be treated in the summer, even mistakenly believe that their own stable condition, and began to recover, the more relaxed the idea of continued treatment. Do you not know that, according to Chinese medicine the dialectical, a lot of chronic kidney disease, chronic nephritis, nephrotic syndrome, all belong to the actual situation mixed, the vacuity of the card. Patients can take advantage of the summer of this favorable opportunity, use of standard means of treatment of certain cold nephropathy, the virtual nephropathy will be able to drive the wind dispelling tonic fitness, to adjust the body's yin and yang balance, a multipliertreatment. This is in fact very simple, as we boil water, under normal circumstances, summer boil a pot of water, certainly better than the winter fast.
Chronic kidney disease, impaired renal intrinsic cells ability to repair itself the highest kidney fibrosis progression is relatively slow. If the patient is able to seize the summer of this favorable opportunity for the treatment of chronic kidney disease, standard treatment of chronic kidney disease, you will be able to receive those who spend less effective, and in stable condition after treatment recurrence.
Therefore, the treatment of chronic kidney disease should seize the favorable opportunity, and early treatment and early rehabilitation. Do not wait until the advent of autumn and winter, the weather cools, human yang latent, relatively low resistance, and again the treatment of chronic kidney disease, when the difficulty of treatment is bound to be greatly enhanced! The reason because of the weather, the patient vulnerable to cold, to the treatment of chronic kidney disease and stable recovery a great deal of variables.
Why summer is the best season for the treatment of chronic kidney disease? Chinese medicine believes that, especially the dog days of summer, as temperatures rise, the human body yang rising, meridian accessible, with plenty of blood, the resistance is relatively high; the same time, the human body in various tissues and organs function, ability to repair itself in a year the best level. At this point, patients with chronic kidney disease often feel "good", the external symptoms of a variety of kidney disease also are relatively mild. Therefore, some patients are often in the summer of their condition "underestimate the enemy," the idea, they do not rush to be treated in the summer, even mistakenly believe that their own stable condition, and began to recover, the more relaxed the idea of continued treatment. Do you not know that, according to Chinese medicine the dialectical, a lot of chronic kidney disease, chronic nephritis, nephrotic syndrome, all belong to the actual situation mixed, the vacuity of the card. Patients can take advantage of the summer of this favorable opportunity, use of standard means of treatment of certain cold nephropathy, the virtual nephropathy will be able to drive the wind dispelling tonic fitness, to adjust the body's yin and yang balance, a multipliertreatment. This is in fact very simple, as we boil water, under normal circumstances, summer boil a pot of water, certainly better than the winter fast.
Chronic kidney disease, impaired renal intrinsic cells ability to repair itself the highest kidney fibrosis progression is relatively slow. If the patient is able to seize the summer of this favorable opportunity for the treatment of chronic kidney disease, standard treatment of chronic kidney disease, you will be able to receive those who spend less effective, and in stable condition after treatment recurrence.
Therefore, the treatment of chronic kidney disease should seize the favorable opportunity, and early treatment and early rehabilitation. Do not wait until the advent of autumn and winter, the weather cools, human yang latent, relatively low resistance, and again the treatment of chronic kidney disease, when the difficulty of treatment is bound to be greatly enhanced! The reason because of the weather, the patient vulnerable to cold, to the treatment of chronic kidney disease and stable recovery a great deal of variables.
Sunday, April 8, 2012
IgA nephritis should be treated?
IgA nephritis should be treated?
The traditional method of treatment of IgA there is no satisfactory treatment options. Of the disease associated with renal insufficiency adrenal corticosteroids with or without immunosuppressants results are not consistent. Recent data suggest that the proteinuria of more than 1g / d, and subjected to every other day medication adrenal cortex hormone beneficial to the improvement of proteinuria. IgA deposition of minimal change nephropathy may alleviate proteinuria. Used in combination with cyclophosphamide, dipyridamole and warfarin to reduce proteinuria and glomerular filtration rate; combined use of cyclosporin A may also reduce proteinuria, and then also reduced creatinine clearance. Efficacy of phenytoin, anti-platelet drugs, the anthocyanin acid disodium diphenyl Sealand due to such drugs is uncertain. Notwithstanding the reports of urokinase may have a role to protect the glomerular filtration rate, but far from conclusive.Recurrent tonsillitis, tonsillectomy may be useful; antibiotics to prevent and treat infections that may be helpful to some acute nephritic syndrome and acute renal failure for the performers. A small series of observations found that the use of fish oil preparations reducing the role of proteinuria and increased glomerular filtration rate.Severe IgA nephropathy (glomerular filtration rate monthly decline 2 ~ 4ml/min) the use of large doses of immune globulin intravenous infusion period, to stop the glomerular filtration rate, improvement of hematuria and proteinuria, but after stopping often relapse.Cases of hypertension and severe proteinuria, glomerular filtration rate of converting enzyme inhibitors may slow down the rate of descent and reduce proteinuria and severe IgA nephropathy, converting enzyme inhibitors are the preferred antihypertensive drugs.Conversion of normal blood pressure, whether effective inhibitors is unclear.
End-stage IgA nephropathy in a kidney transplant, the transplanted kidney happen soon mesangial IgA deposition; subclinical IgA nephropathy if the donor kidney for renal mesangial IgA deposits after implantation of non-IgA nephropathy uremia often rapidly disappearing. Renal transplantation with recurrence does not necessarily progressive renal failure in IgA nephropathy, however Shi after renal transplantation immunosuppressive therapy including cyclosporine A also did not prevent its development. Cadaveric renal transplantation, 1 year and 3-year graft survival up to 87% and 77%, however, individual IgA antibody IgA anti-HLA antigens of renal transplant recipients, 2-year graft survival of up to 100%. reason to believe that these antibodies against HLA antigens played a useful role in increasing graft survival.
Purpura nephritis of Chinese medicine
Allergic purpura nephritis according to clinical manifestations, the purpuric
stage with medicine "spotted" the "spot", associated with kidney damage, and
Traditional Chinese Medicine "Blood" and "edema". The formation of this disease
more than Qiyin weakness, you can not beat evil, resulting in six evils evil
disturbance network, blood sub-volt heat, the spillover skin see purpura, within
infiltration kidney see blood in the urine than
TCM Differential Treatment on the treatment of this disease the main performance of the heat syndrome, advised using the method of detoxification, cooling hemostasis.Performance deficiency, qi and blood, spleen Ning heart, nourish liver and kidney, France. Based on the cause and pathogenesis of this disease, focusing on Qufeng method and the method of blood circulation use of drugs such as search and expel pathogenic wind, black snake, earthworm, white silkworm, the can Qufeng evil, anti-allergy . Blood circulation drugs such as Salvia, Chuanxiong, leeches, etc., can change the blood hypercoagulable state, improve microcirculation, regulate immune function, alleviate immune injury. Blood circulation drugs can also play a role similar to western medicine anticoagulants and compared to the more secure and reliable, no side effects.Several of proprietary Chinese medicine treatment of allergic purpura nephritis as follows: (for reference only, the best medication under the guidance of experts)
Of proprietary Chinese medicine treatment of allergic purpura nephritis:
1, Huang Wan Xijiaodihuang: clearing and detoxifying, cooling blood hemostatic efficacy.For the early stage of the disease is excessive heat to force the blood. Aged 3 to 6 per serving, 1/2 pills, 6 to 9 years per 1 pill, 9 to 12-year-old 1 to 2 pills per serving, served on the 2nd.
Lotus leaf pill: Qingreliangxue stasis hemostatic effect. For the disease early hematuria obvious. 3 to 6 years old per serving, 1/3 pills, aged 6 to 9 1/2 pill per serving, 9 to 12 years of age per serving 2/3 pill, day 2 to 3 times.
3, 100 Po Dan: blood circulation, meridians bleeding effect. For this disease hematuria clearly the blood stasis, meridian Jian astringent. Per serving, 3 to 6-year-old O, 1g, each serving 6 to 9-year-old 0,2 g, 0,3 g, per serving of 12-year-old, 4 hours for 1.
4 Dabuyin pill; the effectiveness of the training of the Qingyuan, nourishing yin. For this disease is a wang. 3 to 6 years old per serving, 1/3 pills, aged 6-9 years per serving, 1/2 pill, 9 to 12 years old each take 1 pill for 3 times.
5, Jishengshenqiwan pill: Warming yang, the effectiveness of the gas lines of the water.For this disease is a kidney decline, to be filled with the cloud overcast. Aged 3 to 6 per serving, 2g, 6 to 9-year-old per serving, 4g, 9 to 12-year-old 6g, each serving 2 to 3 times.
Proprietary Chinese medicines more convenient, but the treatment there are significant limitations. Chinese and Western medicine to their talents, complementary short, Western medicine can play a symptomatic effect of Chinese medicine and micro-penetration therapy of Chinese medicine to cure the root of the same time greatly reduce the side effects of steroids, and thus improve the efficacy, shorten treatment time. Micro therapy for the penetration of traditional Chinese medicine with conventional Western treatment at the same time, the selection of traditional Chinese medicine promoting blood circulation through the network, blood stasis and disinfection, cooling blood detoxification, breeze heat detoxification method of dialectical therapy, achieving a multiplier effect.
Recurring allergic purpura nephritis can aggravate kidney damage, kidney damage is the process of renal fibrosis, allergic purpura nephritis, renal failure or in patients with uremia, renal already appeared in a lot of fibrosis. Micro-based medicine contains an active substance can induce muscle fibroblast apoptosis, to prevent the synthesis of difficult to degrade collagen. Its mechanism of action: TCM active substances in the human body and myofibroblasts molecules closely integrated (combined) molecules bond, fusion, degradation of myofibroblasts, prompting muscle fibroblast cell lysis, broken. Muscle after the cracker broken into fibroblasts by macrophage phagocytosis or pieces removed from the body, which is reached renal fibrosis in the clearance of immune complexes. Muscle fibroblasts were swallowed or discharged, damaged kidney tissue in the role of micro-Chinese medicine slowly to restore kidney function in order to achieve the fundamental purpose of the treatment of renal failure or uremia.
Henoch-Schonlein purpura nephritis, purpura nephritis, renal failure, or purpura nephritis, uremia, whether one should be early treatment and timely treatment. Ill keep in mind must be in a specialized hospital treatment or drug treatment under the guidance of experts.
TCM Differential Treatment on the treatment of this disease the main performance of the heat syndrome, advised using the method of detoxification, cooling hemostasis.Performance deficiency, qi and blood, spleen Ning heart, nourish liver and kidney, France. Based on the cause and pathogenesis of this disease, focusing on Qufeng method and the method of blood circulation use of drugs such as search and expel pathogenic wind, black snake, earthworm, white silkworm, the can Qufeng evil, anti-allergy . Blood circulation drugs such as Salvia, Chuanxiong, leeches, etc., can change the blood hypercoagulable state, improve microcirculation, regulate immune function, alleviate immune injury. Blood circulation drugs can also play a role similar to western medicine anticoagulants and compared to the more secure and reliable, no side effects.Several of proprietary Chinese medicine treatment of allergic purpura nephritis as follows: (for reference only, the best medication under the guidance of experts)
Of proprietary Chinese medicine treatment of allergic purpura nephritis:
1, Huang Wan Xijiaodihuang: clearing and detoxifying, cooling blood hemostatic efficacy.For the early stage of the disease is excessive heat to force the blood. Aged 3 to 6 per serving, 1/2 pills, 6 to 9 years per 1 pill, 9 to 12-year-old 1 to 2 pills per serving, served on the 2nd.
Lotus leaf pill: Qingreliangxue stasis hemostatic effect. For the disease early hematuria obvious. 3 to 6 years old per serving, 1/3 pills, aged 6 to 9 1/2 pill per serving, 9 to 12 years of age per serving 2/3 pill, day 2 to 3 times.
3, 100 Po Dan: blood circulation, meridians bleeding effect. For this disease hematuria clearly the blood stasis, meridian Jian astringent. Per serving, 3 to 6-year-old O, 1g, each serving 6 to 9-year-old 0,2 g, 0,3 g, per serving of 12-year-old, 4 hours for 1.
4 Dabuyin pill; the effectiveness of the training of the Qingyuan, nourishing yin. For this disease is a wang. 3 to 6 years old per serving, 1/3 pills, aged 6-9 years per serving, 1/2 pill, 9 to 12 years old each take 1 pill for 3 times.
5, Jishengshenqiwan pill: Warming yang, the effectiveness of the gas lines of the water.For this disease is a kidney decline, to be filled with the cloud overcast. Aged 3 to 6 per serving, 2g, 6 to 9-year-old per serving, 4g, 9 to 12-year-old 6g, each serving 2 to 3 times.
Proprietary Chinese medicines more convenient, but the treatment there are significant limitations. Chinese and Western medicine to their talents, complementary short, Western medicine can play a symptomatic effect of Chinese medicine and micro-penetration therapy of Chinese medicine to cure the root of the same time greatly reduce the side effects of steroids, and thus improve the efficacy, shorten treatment time. Micro therapy for the penetration of traditional Chinese medicine with conventional Western treatment at the same time, the selection of traditional Chinese medicine promoting blood circulation through the network, blood stasis and disinfection, cooling blood detoxification, breeze heat detoxification method of dialectical therapy, achieving a multiplier effect.
Recurring allergic purpura nephritis can aggravate kidney damage, kidney damage is the process of renal fibrosis, allergic purpura nephritis, renal failure or in patients with uremia, renal already appeared in a lot of fibrosis. Micro-based medicine contains an active substance can induce muscle fibroblast apoptosis, to prevent the synthesis of difficult to degrade collagen. Its mechanism of action: TCM active substances in the human body and myofibroblasts molecules closely integrated (combined) molecules bond, fusion, degradation of myofibroblasts, prompting muscle fibroblast cell lysis, broken. Muscle after the cracker broken into fibroblasts by macrophage phagocytosis or pieces removed from the body, which is reached renal fibrosis in the clearance of immune complexes. Muscle fibroblasts were swallowed or discharged, damaged kidney tissue in the role of micro-Chinese medicine slowly to restore kidney function in order to achieve the fundamental purpose of the treatment of renal failure or uremia.
Henoch-Schonlein purpura nephritis, purpura nephritis, renal failure, or purpura nephritis, uremia, whether one should be early treatment and timely treatment. Ill keep in mind must be in a specialized hospital treatment or drug treatment under the guidance of experts.
Saturday, April 7, 2012
Mesangialproliferative glomerulonephritis treatment
The disease caused by nephrotic syndrome is often more difficult. Small doses the next day prednisone therapy may help to improve renal function. West et al use the next day oral steroids long-term treatment, biopsy before and after treatment, the results prove this method is conducive to the survival of the kidney. At present, most nephrologists only symptomatic treatment.
Treatment of type Ⅰ, in addition to glucocorticoids, but also with other drugs such as immune suppression drugs and anticoagulants.
MPGN patients of all ages, with normal renal function showed only mild asymptomatic proteinuria without receiving steroids, immunosuppressive drug therapy. Only every 3 to 4 months follow-up, close observation of renal function, proteinuria and blood pressure control. Adults and children with primary MPGN patients, urinary protein> 3g / d, renal damage and biopsy of renal interstitial disease may be given hormones, immunosuppressive drug therapy.
May be effective in the treatment of 6 to 12 months for proteinuria (> 3g / d) or impaired renal function in children with primary MPGN patients, large doses of glucocorticoids next day 40mg/m2. If that does not stop taking glucocorticoids, we recommend close follow-up, focusing on conservative treatment (ie, control of blood pressure, applied to reduce urinary protein drugs and correction of metabolic disorders).
Proteinuria (> 3g / d) or adults with impaired renal function in patients with primary MPGN, should be given aspirin (325mg / d), dipyridamole (dipyridamole) treatment (75 to 100mg, 2 times / d), or both combined 12 months if the treatment plan is invalid is disabled. Great importance to be able to slow the decline in kidney function factors and close follow-up should be part of the treatment plan.
Several treatment studies have reported the next day, or daily oral corticosteroids, intravenous high-dose glucocorticoids, and the combined application of the results: a more rigorous research confirmed: children MPGN, hormone therapy in slowing renal ball filtration rate (GFR) decline in the effective and stable renal function. Most of the 80 cases were type Ⅰ MPGN, prednisone (prednisone) 40mg/m2 every other day oral average treatment time of 13 months, 61% of treatment group children at the research stage renal stable, while The placebo group only 12%. Proved children MPGN patients with glucocorticoid is effective. Studies have shown that children's of MPGN early application of high-dose prednisone (prednisone) can effectively shorten the course of the disease. But remains controversial, still with a rigorous randomized controlled trials to verify.
Danadio and other study dipyridamole (dipyridamole), aspirin and warfarin in MPGN treatment on renal outcome (including the impact of urinary protein excretion rate) and platelet half-life (bleeding tendency). Lower urinary protein excretion rate, but no significant changes in GFR. Cattran and other 59 cases of MPGN patients taking cyclophosphamide, warfarin and dipyridamole (dipyridamole) the efficacy of the treatment time of 18 months. The detailed description of how the research only I MPGN patients will have a clearer treatment of type Ⅱ disease is not strong enough evidence to conclude.
Type Ⅱ there is no effective treatment. Reasonable solution to the treatment of this disease is still controversial, treatment options should carefully weigh the efficacy of the treatment of adverse reactions. Leaves any higher recommended using the following program: dipyridamole (dipyridamole) 50 ~ 300mg / d, divided into three doses. If nephrotic syndrome, the available symptomatic of the way and try the standard regimen of hormones, to be tapered to maintenance dose (the next day morning serving Dayton prednisone 0.4mg/kg), and then to maintain the application a longer period, such ashave high blood pressure, it is recommended to use the new staircase method antihypertensive therapy. In the implementation of treatment programs should be closely observed side effects, to exceed and achieve therapeutic effect.
Other treatment, including lipid-lowering, ACE inhibitors, the ARB, low molecular weight heparin, in recent years, scholars have reported that mycophenolate mofetil (MMF) treatment of the disease, showing initial results, but the number of cases was small, and the lack of control and long-term observational study.
In addition, the application of cytotoxic drugs, plasmapheresis methods, traditional Chinese medicine treatment in some studies the treatment of some efficacy.
In deciding what type of patients when the treatment, the clinician must consider the pros and cons of the expected course and outcome of the disease, and treatment, renal insufficiency development and drug treatment due to poor compliance.
Wednesday, March 21, 2012
What are the methods of Chinese medicine treatment of diabetic nephropathy
①diabetic nephropathy TCM treatment should be heat and dampness, promoting blood circulation. In the basic treatment (including blood sugar control, treatment of hypertension, low salt, high-quality low-protein diet) at the same time with the TCM syndrome differentiation, treatment of diabetic nephropathy, the rational application of Qingrejiedu Dampness, eliminate and alleviate the damp heat evil, inhibition of renal immune inflammation, reduce proteinuria and to promote the repair of kidney disease, thereby improving renal function, and control the progress of this disease have a positive role. Focus on blood circulation in the treatment, especially patients with chronic illness, emphasizing the chronic illness must be active.
② TCM treatment of diabetic nephropathy in drug administration, on the one hand, should pay attention to adjust the patient's immune function, Chinese medicine is the benefit of drug application, for example, can be used: qi ginseng, Astragalus, Codonopsis, Sijunzitang, Buzhongyiqitang. The nourishing Class cinnamon, pilose antler, Cordyceps sinensis, Psoralea, Cistanche, Ba Wei Di Huang balls. On the other hand, should be taken to avoid the use of renal toxic effects of traditional Chinese medicine, such as manshuriensis Han fangchi, cantharidin, bee venom, motherwort.
③ diabetic nephropathy (DN), Western medicine in the treatment of certain limitations and adverse effects, especially long-term use will have considerable side effects in the liver and kidney more than eight years. Chinese medicine syndrome is a means of effective prevention and treatment of diabetic nephropathy. The man in the field of prevention and treatment of diabetic nephropathy concern, especially the advantages of the good efficacy in the prevention and treatment of early diabetic nephropathy and reduce adverse reactions, making it an important means of intervention.
These are the traditional Chinese medicine treatment of diabetic nephropathy in patients with diabetic nephropathy, their islet and kidney cells are subject to damage. Targeting Chinese living pancreatic infiltration therapy by drugs active ingredients fully release and mixed after the effective penetrant and infiltration devices, the active ingredients of drugs enter the lesion, in order to repair the damaged cells, so that diabetes re-kidney patients with insulin secretion, and elimination of insulin resistance; targeting Chinese medicine living pancreatic infiltration therapy to repair damaged kidneys, blocking and reversal of renal fibrosis cells, maximum repair the kidneys, so that diabetic nephropathy The patients gradually recover.
How treatment of latent glomerulonephritis
Occult how the treatment of glomerulonephritis. How the treatment of
crescentic glomerulonephritis, crescentic glomerulonephritis? Suffering from how
the treatment of crescentic glomerulonephritis? Crescentic glomerulonephritis
good governance? For the crescent The glomerulonephritis doubt, we do a brief
explanation. The glomerulonephritis experts explain glomerulonephritis how
treatment "question. Specific latent glomerulonephritis how treatment related
content follows.
Occult glomerulonephritis how treatment recommended:
Sentence stove proliferative glomerulonephritis how the treatment of glomerulonephritis two years how the treatment of how the treatment of glomerulonephritis, how the treatment of chronic glomerular nephritis how the treatment of chronic glomerulonephritis occult blood? How the treatment of glomerulonephritis
How the treatment of chronic interstitial glomerulonephritis? Daily therapeutic use of antibiotics or hormones and other drugs for the treatment of chronic interstitial glomerulonephritis, to play the anti-inflammatory effects of drugs, for the interstitial glomerulonephritis spondylitis patients in renal tubular epithelial cell damage in the initial stage of treatment, but deep into the peritubular cells, interstitial fibroblasts and glomerular damage, the force and the drug is not reached, can not implementation of an effective and radical treatment. Occult how the treatment of glomerulonephritis. Suffering from chronic glomerulonephritis and how treatment? Suffering from chronic glomerulonephritis and how treatment? How the treatment of chronic glomerulonephritis? Inappropriate treatment measures can control the disease, but once infection, the disease will attack, but also showed a worsening trend appears serum creatinine (creatinine) (Cr), blood urea nitrogen began increased, renal hypertension, renal anemia, and other symptoms generally indicates kidney fibrosis range expansion, and gradually spread to the entire kidney, less and less healthy cells of the inherent, gradually increased extracellular matrix deposition, rapid deterioration of renal function, but is still at a reversible stage, seize the timing of treatment, the maximum protection to the kidney unit.
Occult glomerulonephritis how treatment, and how the treatment of glomerulonephritis.The phenomenon of hematuria in children must be to arouse the attention of parents, and treatment of children with hematuria how treatment must not be blind, children with acute glomerulonephritis in children accounted for the urinary system diseases of hospitalized children first, its rapid onset, often hematuria, urine, proteinuria, edema and hypertension and other symptoms. The most common glomerulonephritis, acute hemolytic streptococcus infections. Pathogens invade the body, stimulate the body to produce antibodies, the antigen composition of the bacterial surface with antibody binding to generate antigen-antibody complex deposition in the glomerular basement membrane caused immune damage and inflammation, leading to the basement membrane rupture, the glomerular capillary increased permeability of the glomerular filtration rate, hematuria, proteinuria, anuria and edema, in turn causing high blood pressure, serious people with severe circulatory congestion, varying degrees of renal damage and hypertensive encephalopathy , and the immune response can produce anaphylatoxin, resulting in the increase in systemic capillary permeability, increased edema.
Occult how the treatment of glomerulonephritis. How the treatment of chronic nephritis (chronic glomerulonephritis) was that many patients feel very helpless, the occurrence of this disease, there are many kinds of understanding of the clinical classification of chronic nephritis (chronic glomerulonephritis) treatment of the disease is a great help, chronic glomerulonephritis most hidden onset, long duration, the condition is more than the slow progress of different pathological types, clinical manifestations are inconsistent, the present symptoms in most cases led to edema of varying severity. light only the face and lower extremity slightly swollen, and might appear nephrotic syndrome (NS), and in some cases, while hypertension, led by the current symptoms and found that for chronic glomerulonephritis. can also be manifested as asymptomatic proteinuria and / orhematuria. or only appear polyuria and nocturia, or no obvious physical decline until the emergence of severe anemia or uremia as the first symptom in the whole course.
How the treatment of glomerulonephritis. The solution of micro-Chinese medicine and how the occult glomerulonephritis treatment by many patients sought after cases if you are still for these diseases to worry about, you can use these methods, but be sure to choose a regular hospital. x
Micro-based medicine is to determine the specific medication drugs processed ultrafine grinding mixing the release of drug activity factor, kidney acupoints, with the effective penetrant and infiltration devices, ultra-light penetration through the skin capacity and medicine, meridian principle penetration of the active factor of the drug directly to the lesions of the kidney system standard treatment for injured lesions, vasodilator, anti-inflammatory, anti-thrombotic, anti-blood viscosity, degradation of the four functions of the extracellular matrix treatment, as long as the organizational structure functional recovery in place, will return to its corresponding function, your disease naturally be able to get a good treatment.
Occult glomerulonephritis how treatment recommended:
Sentence stove proliferative glomerulonephritis how the treatment of glomerulonephritis two years how the treatment of how the treatment of glomerulonephritis, how the treatment of chronic glomerular nephritis how the treatment of chronic glomerulonephritis occult blood? How the treatment of glomerulonephritis
How the treatment of chronic interstitial glomerulonephritis? Daily therapeutic use of antibiotics or hormones and other drugs for the treatment of chronic interstitial glomerulonephritis, to play the anti-inflammatory effects of drugs, for the interstitial glomerulonephritis spondylitis patients in renal tubular epithelial cell damage in the initial stage of treatment, but deep into the peritubular cells, interstitial fibroblasts and glomerular damage, the force and the drug is not reached, can not implementation of an effective and radical treatment. Occult how the treatment of glomerulonephritis. Suffering from chronic glomerulonephritis and how treatment? Suffering from chronic glomerulonephritis and how treatment? How the treatment of chronic glomerulonephritis? Inappropriate treatment measures can control the disease, but once infection, the disease will attack, but also showed a worsening trend appears serum creatinine (creatinine) (Cr), blood urea nitrogen began increased, renal hypertension, renal anemia, and other symptoms generally indicates kidney fibrosis range expansion, and gradually spread to the entire kidney, less and less healthy cells of the inherent, gradually increased extracellular matrix deposition, rapid deterioration of renal function, but is still at a reversible stage, seize the timing of treatment, the maximum protection to the kidney unit.
Occult glomerulonephritis how treatment, and how the treatment of glomerulonephritis.The phenomenon of hematuria in children must be to arouse the attention of parents, and treatment of children with hematuria how treatment must not be blind, children with acute glomerulonephritis in children accounted for the urinary system diseases of hospitalized children first, its rapid onset, often hematuria, urine, proteinuria, edema and hypertension and other symptoms. The most common glomerulonephritis, acute hemolytic streptococcus infections. Pathogens invade the body, stimulate the body to produce antibodies, the antigen composition of the bacterial surface with antibody binding to generate antigen-antibody complex deposition in the glomerular basement membrane caused immune damage and inflammation, leading to the basement membrane rupture, the glomerular capillary increased permeability of the glomerular filtration rate, hematuria, proteinuria, anuria and edema, in turn causing high blood pressure, serious people with severe circulatory congestion, varying degrees of renal damage and hypertensive encephalopathy , and the immune response can produce anaphylatoxin, resulting in the increase in systemic capillary permeability, increased edema.
Occult how the treatment of glomerulonephritis. How the treatment of chronic nephritis (chronic glomerulonephritis) was that many patients feel very helpless, the occurrence of this disease, there are many kinds of understanding of the clinical classification of chronic nephritis (chronic glomerulonephritis) treatment of the disease is a great help, chronic glomerulonephritis most hidden onset, long duration, the condition is more than the slow progress of different pathological types, clinical manifestations are inconsistent, the present symptoms in most cases led to edema of varying severity. light only the face and lower extremity slightly swollen, and might appear nephrotic syndrome (NS), and in some cases, while hypertension, led by the current symptoms and found that for chronic glomerulonephritis. can also be manifested as asymptomatic proteinuria and / orhematuria. or only appear polyuria and nocturia, or no obvious physical decline until the emergence of severe anemia or uremia as the first symptom in the whole course.
How the treatment of glomerulonephritis. The solution of micro-Chinese medicine and how the occult glomerulonephritis treatment by many patients sought after cases if you are still for these diseases to worry about, you can use these methods, but be sure to choose a regular hospital. x
Micro-based medicine is to determine the specific medication drugs processed ultrafine grinding mixing the release of drug activity factor, kidney acupoints, with the effective penetrant and infiltration devices, ultra-light penetration through the skin capacity and medicine, meridian principle penetration of the active factor of the drug directly to the lesions of the kidney system standard treatment for injured lesions, vasodilator, anti-inflammatory, anti-thrombotic, anti-blood viscosity, degradation of the four functions of the extracellular matrix treatment, as long as the organizational structure functional recovery in place, will return to its corresponding function, your disease naturally be able to get a good treatment.
Tuesday, March 20, 2012
Governance experience in the one case of focal proliferative sclerosing IgA nephropathy
Patients with Zhou, male, 42 years old, newly diagnosed on January 22, 2010. The main reason: proteinuria, hematuria 1 month to diagnosis. Patients 1 month before the examination found that urinary protein, occult blood, and many times at the Peking University First Hospital, Xiyuan Hospital of review were seen hematuria, proteinuria, were not system diagnosis and treatment. Wear said: Dongzhimen Hospital, kidney renal biopsies showed 40 glomerular five global sclerosis, 4 ischemic sclerosis, two segmental glomerular sclerosis, the rest of glomerular mesangial cells and matrix light todegree of diffuse hyperplasia, focal segmental severe increase mesangial addicted complex red protein deposition, tubular epithelial vacuoles and granular degeneration, spotty atrophy, multiple foci of the renal mass-like lymph nodes and mononuclear cell infiltration with fibrosis, wall thickening of small arteries, in line with: Home stove proliferative sclerosing IgA nephropathy. Check: 24-hour urine protein excretion 1.76g; protein, occult blood; of creatinine 165.3umol / L, urea nitrogen 8.38mmol / L Blood pressure: 120/80mmHg, oral Aprovel 150mg 1, the pressure's up to 5mg day control of blood pressure. Zheng Jian: fatigue, mouth bitter stick, irritability, foamy urine, lumbar pain, stool viscosity, when the stool, no fever, cough, sputum, lower extremity edema, is satisfied that the poor sleep can red tongue, yellowish greasy, slippery pulse. Diagnosis: focal proliferative sclerosing IgA nephropathy, renal insufficiency, decompensated; hypertension in three high-risk groups. TCM diagnosis: kidney slow wind syndrome is a qi deficiency and liver stagnation and heat block the kidney by blood stasis paralysis.Governing Law: Qi stagnation, heat and dampness, Huoxuetongluo. Recipe: raw Astragalus 50g, the bupleurum 15g, turmeric 15g skullcap 15g, gardenia Health 15g, France Pinellia 10g raw barley 30g, lotus leaf 15g, earthworm 20g, silkworm 20g, raw citrus aurantium 15g, fried betel nut 30g Sophora japonica 15g, Health Burnet 30g, contact Ishido 15g, Atractylodes 20g, Treats 15g, 6 a casual 30g. 7 water, a daily, morning and evening hours service. Antihypertensive drugs to control blood pressure following the service.
29: two clinics in January, fatigue, backache relief, urinary Mo reduced, still upset, irritability, mouth bitter stick, the big can. Red tongue, yellow greasy moss, pulse string.Urine: protein, erythrocyte :10-15 / HP. Stool disappeared, still proteinuria, suggesting that reduce the blood heat; renal wear visible part of the glomerular ball, segmental sclerosis and ischemic sclerosis, renal interstitial multiple spotty fibrosis, Chinese interpreted as network interest into the plot, I strengthen Poxue Xiaozheng products.Recipe: the cases of newly diagnosed party to Huaihua, Health Burnet, plus triangular 15g, Curcuma 15g, Chuan Xiong 18, Smilax glabra 50g in order to strengthen the power of of detoxification Poxue Xiaozheng.
3 attending February 12th: The patient complaint when hypochondriac pain, lumbar pain disappeared, I no obvious discomfort, red tongue, yellow greasy moss, pulse string. 24-hour urinary protein excretion: 0.47g; creatinine: 140umol / L, urea nitrogen 7.9mmol / L,.Prompts the liver qi stagnation, not General pain. Go to the top of a lotus leaf, network Ishido, Yuan Hu 15g, Toosendan 12g Liver Qi to relieve pain.
4 attending March 1: The patient complained of sore throat, irritability, mouth bitter sticky, sticky stool, dark tongue, yellow greasy moss, pulse string. Urine: protein -, 3 - to 5 red blood cells. Show the wind poison off the pharynx into the network, the liver heat.Recipe: the bupleurum 15g, skullcap 15g, Health and gardenia 15g, gentian 10g raw barley 20g, Agastache 15g, Folium 30g, forsythia 15g of Fritillaria 15g, Shegan 15g Mint 15g, Shichangpu 15g earthworm 20g, silkworm 20g, bellflower 15g, the Chuanxiong 18g, black snake 15g, contact Ishido 15g, raw licorice 6g to detoxification LiYan, found the wind Tongluo Soothing heat and dampness.
5 clinic March 15: patients with sore throat disappeared, irritability, mouth bitter sticky stool viscosity. Dark tongue, yellow greasy moss, pulse string. 24-hour urinary protein excretion: 0.41g; the creatinine 115umol / L, urea nitrogen 6.4mmol / L,. . Recipe: top to Agastache, Fritillaria the Shegan, Folium, Fritillaria, Platycodon, the addition pinellia 10g, the Coptis 9g, the Magnolia 9g, lotus leaf 15g, Perrin 15g strengthening heat dampness.
6 attending March 29: patients with stable disease, mouth bitter sticky, no other obvious discomfort, dark tongue yellowish greasy moss, pulse strings. Urine: (-); Biochemical: (-).The cases above the white cardamom 10g continue to take medication.
Thereafter follow-up year, with no discomfort. Urinalysis, blood biochemistry were normal.
IgA nephropathy is one of the world's most common primary glomerular diseases, glomerular mesangial IgA deposition of immunoglobulin, IgA with C3 granular deposition in the mesangial area diseases. IgA nephropathy can be expressed for a variety of different forms of pathology, focal proliferative sclerosing IgAN in the IgAN in a certain proportion, and pathological changes mainly as a glomerular mesangial cell proliferation, extracellular matrix hyperplasia, severe pathological damage can varying degrees of glomerulosclerosis, tubular atrophy, interstitial fibrosis, easy hematuria, proteinuria, edema, hypertension, and renal function decline, if left untreated, can eventually lead to end-stage renal failure ( of ESRD).
How does Micro-Chinese Medicine Osmotherapy Treat Hypertensive Nephropathy
Micro-Chinese Medicine Osmotherapy now is a creative and effective therapy
for Hypertensive Nephropathytreatment. On the one hand, this therapy will
improve the situation of various kinds of blood vessels in accordance with the
characteristics of Hypertensive Nephropathy; on the other hand, it also could
repair the damaged intrinsic cells of kidneys, realizing the goal of treating
Hypertensive Nephropathy fundamentally.
The following are detailed introduction of these two aspects:
I.improve various kinds of blood vessels and decrease the blood pressure fundamentally.
There are a large number of relaxing factors of blood vassal in superfinely-shattered Chinese Medicines, which will permeate into small vessels and play a synergistic effect together with vessel-tension factors, and the effect of these is to relax the blood vessels around the body and kidneys. So it could remit the high blood pressure caused by poor and overstrain vasodilation.
II.repair the damaged nephrons, improve kidney function
Once Micro-Chinese Medicine is permeated into patients’ body, the effective medicines will directly permeate into kidney lesions (aiming at immune complexes and sclerosing glomeruli etc.). It will release Chinese Medicine’s active substances to repair pathological tissues and immune complexes. The function of kidneys will begin to recover when the kidneys are repaired. That is the way Micro-Chinese Medicine Osmotherapy Treat Hypertensive Nephropathy. On the treatment of Uremia and Hypertensive Nephropathy, Micro-Chinese Medicine Osmotherapy is not only fast in curative effect but also not easily to relapse.
The following are detailed introduction of these two aspects:
I.improve various kinds of blood vessels and decrease the blood pressure fundamentally.
There are a large number of relaxing factors of blood vassal in superfinely-shattered Chinese Medicines, which will permeate into small vessels and play a synergistic effect together with vessel-tension factors, and the effect of these is to relax the blood vessels around the body and kidneys. So it could remit the high blood pressure caused by poor and overstrain vasodilation.
II.repair the damaged nephrons, improve kidney function
Once Micro-Chinese Medicine is permeated into patients’ body, the effective medicines will directly permeate into kidney lesions (aiming at immune complexes and sclerosing glomeruli etc.). It will release Chinese Medicine’s active substances to repair pathological tissues and immune complexes. The function of kidneys will begin to recover when the kidneys are repaired. That is the way Micro-Chinese Medicine Osmotherapy Treat Hypertensive Nephropathy. On the treatment of Uremia and Hypertensive Nephropathy, Micro-Chinese Medicine Osmotherapy is not only fast in curative effect but also not easily to relapse.
The Best Time for Treating Diabetic Nephropathy
Actually, in treating Diabetic Nephropathy, the earlier the treatment is, the better the curative effect will be, for with the worsening of the kidney damages, the treatment and the prognosis will correspondingly become more difficult.
Both the occurrence and the development of Diabetic Nephropathy are the process of the accumulation of kidney damages. Clinically, Diabetic Nephropathy can be divided into five stages. Generally, if the blood sugar did not get good control, Type 1 Diabetes will progress one stage every five years, while Type 2 Diabetes will progress one stage every three or four years.
Stage 1 to Stage 3 all belong to the early stage of Diabetic Nephropathy. In these three stages, usually there is no symptoms. If effective treatment can be adopted in these stages, Stage 1 Diabetic Nephropathy can be cured, while the progression of Stage 2 or 3 Diabetic Nephropathy can be obviously suppressed. In stage 1, only the glomerular filtration rate(GFR) increases, therefore, if the blood sugar can be controlled well, the patients' condition can be reversed. In stage 2 and 3, microalbumin will occur in the urine. If the microalbumin only occurs after exercise, fever or in other stress state, it is stage 2 Diabetic Nephropathy; if the microalbumin occurs persistently, it is stage 3 Diabetic Nephropathy. In treating stage 2 and 3 Diabetic Nephropathy, apart from controlling the blood sugar, angiotensin converting enzyme inhibitor(ACEI) and angiotensin receptor blockers(ARB) should also be adopted.
By urine routine test, if the urine protein is positive, it indicates the coming of stage 4 Diabetic Nephropathy. In this stage, the urine protein will increase and finally form large quantities of proteinuria(the urine protein is more than 3.5 g/d), which will lead to hypoproteinemia, edema and hyperlipidemia. That is to say, patients with stage 4 Diabetic Nephropathy will have Nephrotic Syndrome, often with hypertension. At this time, the renal function will get worse quickly. And as for treatment, it is mainly symptomatic treatment, including limiting the salt intake, promoting the urination, lower the blood pressure and regulating the blood lipid.
If the patients' condition continue to worsen, it will develop into the stage 5 Diabetic Nephropathy—the Kidney Failure period. In this stage, the patients will have poor appetite, nausea, vomit and other symptoms, and their serum creatinine and blood urea nitrogen will increase. And finally, in order to sustain life, dialysis will be necessary for some patients.
From the above, we can conclude that stage 1 to stage 3 is the best time for prolonging the progression of Diabetic Nephropathy.
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