Children with IgA nephropathy renal damage which several types?

IgA nephropathy (1gAGN) is a group associated with system disease, renal biopsy immune pathology in glomerular mesangial granular deposition of IgA-based disease.IgAGN for the pathological diagnosis of an immune name, clinical glomerulonephritis with hematuria as the main manifestation, but also led to one of the main end-stage renal failure. That the Department of an independent clinical a pathological syndrome. Renal damage following types:
First, episodes of gross hematuria
Often in a variety of respiratory tract infections in 1-3d after gross hematuria, it is also known as pharyngitis synchronization hematuria, this common sense of acute chain glomerulonephritis. Deformability of urinary red cell morphology, suggestive of glomerular hematuria. I have seen homes in addition to gross hematuria, and in some cases accompanied by the waist and (or) severe abdominal pain, often misdiagnosed as urinary calculi, acute abdomen (appendicitis). Such abdominal pain mechanism may be associated with inflammatory lesions of small arteries in the ureter or gastrointestinal mucosa manifestations of systemic small vessel vasculitis lesions. In addition, the electron microscope shows submucosal small artery injury was fibrinoid necrosis, IgA, and C3, and fibrin deposition to support IgAGN gastrointestinal tract has also been compromised. Low back pain associated with urinary retention or temporary oliguria may be of small blood clots occur in the urinary tract caused by a temporary obstruction.
Second, the nephrotic syndrome
Individually or in some cases associated with hypertension, hematuria. If the histopathological glomerular sclerosis and renal vascular sclerosis poor prognosis.Shanghai Children's Hospital have reported 20 cases IgAGN, which manifested as nephrotic-type, 9 cases (47%), showing that this type of a certain proportion of children IgAGN.
Third, the nephritic syndrome
This type of performance with / without mild edema of asymptomatic microscopic hematuria, often misdiagnosed as the chain sense glomerulonephritis more common in urine screening examination and confirmed by biopsy.
Fourth, the simple proteinuria
Proteinuria as the first symptom in the pediatric majority showed mild or moderate proteinuria without edema and other symptoms of kidney damage.
Fifth, rapidly progressive glomerulonephritis
Rare. Continuous gross hematuria, proteinuria associated with heart, brain involvement, the abrupt deterioration of short-term renal function, renal biopsy widely (50% -100%) glomerular crescent form. Severe hematuria hemoglobin on renal tubular toxicity and tubular obstruction with acute tubular necrosis.