Had chronic nephritis can be much longer this disease can be cured? Chronic nephritis, short for chronic glomerulonephritis, can be transformed from acute nephritis, the disease is quite stubborn, clinically complete cure is considerably more difficult. Some patients with chronic nephritis it very serious thought to be life threatening, there would be a "chronic nephritis can be much longer" questions, in fact, chronic nephritis that you did not think that serious, as long as the development of renal failure , uremia, is not life-threatening, so worry much longer is not necessary. In the case of patients with chronic nephritis, should ask is "chronic nephritis can be cured?" What methods can solve the problem of no recurrence!
What can cure chronic nephritis, even to the radical no recurrence of the purpose? The treatment of chronic nephritis is a gradual process, need to be persistent, and all those responsible for hospitals, doctors and patients should follow the objective law, not engage in the "Great Leap Forward" in the course of the treatment of chronic nephritis.
Lead to either chronic nephritis or other kidney disease, the reason is that of progression of kidney fibrosis injury, destruction of renal cell structure damage of the glomerular cell function. The cell structure was fibrosis of damage and failure is the root cause of various types of kidney disease, "this", due to functional damage caused by proteinuria, serum creatinine increased "standard".
Micro-based medicine to penetrate the treatment of chronic nephritis different from the other in order to reduce urinary protein excretion, lower creatinine of the "standard" the next big effort, but the micro-through from the start the factors leading to renal fibrosis - kidney disorders, ischemic , hypoxic began.
Treatment of chronic nephritis need treatment for impaired renal intrinsic cells from the fundamental blocking renal fibrosis process, fundamentally, the infiltration therapy of micro-based traditional Chinese medicine mainly play the following role to get treatment!Specific description is as follows:
1.Vasodilators: of micro-penetration therapy of Chinese medicine through effective Chinese medicines dilate blood vessels, effectively improve renal ischemia and hypoxia, and to provide more oxygen and blood for the kidneys, so as to better accelerate the repair of renal intrinsic cells.
2.micro therapy for the penetration of traditional Chinese medicine through the anti-inflammatory, anticoagulant to inactivate inflammatory factors, and virulence factors of renal fibrosis process, and to prevent blood clots, blood clotting occurs, further blocking renal fibrosis, and repair damaged of renal intrinsic cells.
3.Also note that for the treatment of chronic nephritis immunosorbent assay, clear the immune complexes of patients' bodies to provide a secure and stable environment within the patients with late repair.
Through the rational application of the above treatment, the mesangial cells of the glomerular capillary repair, will be natural recovery of its normal physiological function.Mesangial cells of the barrier function will receive a reply, after the recovery of these functions, protein and other clinical symptoms also vanish. Effective treatment of chronic nephritis, to achieve true "cure disease before treatment, the disease is cured cases from extinction, so as to effectively prevent relapse.
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Showing posts with label Chronic nephritis Treatment. Show all posts
Showing posts with label Chronic nephritis Treatment. Show all posts
Thursday, April 19, 2012
Friday, April 13, 2012
How to control the hypertension of patients with chronic nephritis?
Chronic nephritis, the residual and (or) had lesions of the renal unit in
compensatory hemodynamic status, systemic hypertension will undoubtedly add to
this condition, leading to glomerular injury, and therefore patients with
chronic nephritis should be actively controlled high blood pressure, prevent
deterioration of renal function.
In recent years, through a series of studies confirmed that most scholars have angiotensin converting enzyme inhibitors as first-line antihypertensive drugs. Lately, a lot of clinical studies confirmed that calcium antagonists such as nifedipine, nicardipine equal treatment of hypertension and renal function deterioration is more positive effect.That calcium antagonists, despite the slight expansion of the role of afferent arterioles, but it has significantly reduced the role of systemic blood pressure, so make the uninvolved or only partially involved glomerular hemodynamics, the high metabolic statusbe improved; In addition, calcium channel blockers reduce oxygen consumption, inhibition of platelet aggregation through the membrane effect of reducing the excessive oxidation of the calcium in the interstitial deposition and reduce the cell membrane, so as to achieve to reduce kidney damage and stable renal function. Clinical reports, short-term (4 weeks) or long (1-2 years) with calcium antagonist treatment of nephritis in patients with chronic renal insufficiency has not revealed any glomerular injury, but clearly demonstrated that it is angiotensin converting enzyme inhibitors is very similar to the efficacy of renal function deterioration. And angiotensin converting enzyme inhibitors at lowering urinary protein role for it in general. It should be noted that some scholars believe that the calcium antagonists impact on renal function is still a need for more long-term observation.
β-blockers, such as the United States and more peace of mind, Atenolol, has a good effect on the renin-dependent hypertension. beta-blockers reduce renin, although the drug reduce cardiac output, but does not affect renal blood flow and GFR, it is also used for the treatment of renal hypertension. It should be noted that some beta-blockers such as atenolol and naphthalene hydroxyl peace of mind, low-fat-soluble, since renal excretion, so renal insufficiency should pay attention to adjust the dose and extending administration time.
In addition, vasodilators such as hydralazine antihypertensive effect, it can be combined with beta-blockers reduce vasodilators stimulate renin angiotensin system side effects (such as rapid heartbeat, water and sodium retention ), and may improve the therapeutic effect. Hydralazine general daily 200mg, but must be alert to the possibility of drug-induced lupus erythematosus-like syndrome.
Edema renal, can add to a thiazide diuretic; poor renal function (serum creatinine> 200μmol / L), thiophene triazine efficacy or invalid, it should use loop diuretics marrow .Chronic nephritis patients treated with diuretics should be noted that the electrolyte imbalance in the body, and to pay attention to the tendency to aggravate hyperlipidemia, hypercoagulable state.
In recent years, through a series of studies confirmed that most scholars have angiotensin converting enzyme inhibitors as first-line antihypertensive drugs. Lately, a lot of clinical studies confirmed that calcium antagonists such as nifedipine, nicardipine equal treatment of hypertension and renal function deterioration is more positive effect.That calcium antagonists, despite the slight expansion of the role of afferent arterioles, but it has significantly reduced the role of systemic blood pressure, so make the uninvolved or only partially involved glomerular hemodynamics, the high metabolic statusbe improved; In addition, calcium channel blockers reduce oxygen consumption, inhibition of platelet aggregation through the membrane effect of reducing the excessive oxidation of the calcium in the interstitial deposition and reduce the cell membrane, so as to achieve to reduce kidney damage and stable renal function. Clinical reports, short-term (4 weeks) or long (1-2 years) with calcium antagonist treatment of nephritis in patients with chronic renal insufficiency has not revealed any glomerular injury, but clearly demonstrated that it is angiotensin converting enzyme inhibitors is very similar to the efficacy of renal function deterioration. And angiotensin converting enzyme inhibitors at lowering urinary protein role for it in general. It should be noted that some scholars believe that the calcium antagonists impact on renal function is still a need for more long-term observation.
β-blockers, such as the United States and more peace of mind, Atenolol, has a good effect on the renin-dependent hypertension. beta-blockers reduce renin, although the drug reduce cardiac output, but does not affect renal blood flow and GFR, it is also used for the treatment of renal hypertension. It should be noted that some beta-blockers such as atenolol and naphthalene hydroxyl peace of mind, low-fat-soluble, since renal excretion, so renal insufficiency should pay attention to adjust the dose and extending administration time.
In addition, vasodilators such as hydralazine antihypertensive effect, it can be combined with beta-blockers reduce vasodilators stimulate renin angiotensin system side effects (such as rapid heartbeat, water and sodium retention ), and may improve the therapeutic effect. Hydralazine general daily 200mg, but must be alert to the possibility of drug-induced lupus erythematosus-like syndrome.
Edema renal, can add to a thiazide diuretic; poor renal function (serum creatinine> 200μmol / L), thiophene triazine efficacy or invalid, it should use loop diuretics marrow .Chronic nephritis patients treated with diuretics should be noted that the electrolyte imbalance in the body, and to pay attention to the tendency to aggravate hyperlipidemia, hypercoagulable state.
Angiotensin converting enzyme inhibitors for patients with chronic nephritis What is the significance?
In recent years by a large number of animal experiments and nephritis in
patients with controlled clinical observation has been confirmed, unless there
are certainly antihypertensive efficacy of the drug can reduce glomerular
pressure, there is certainly delay the deterioration of renal function, lower
urinary protein (20% to 40%) and reduce the role of glomerular sclerosis.
Commonly used preparations the mercapto tensiomin proline acid, typical doses of
25 to 50 mg / 3 times a day, clinical; without thiol according to Na Puli, the
long duration of action, the commonly used dose of 5 to 10 mg / day 1.The drugs
to reduce the main mechanism of ball pressure, protect and stabilize the renal
function as follows:
① The expansion of glomerular artery, small arteries of the ball is more significant than the afferent artery dilation, and therefore reduce the pressure inside the ball, reducing renal ball high blood dynamics;
② The angiotensin II-stimulated proximal tubular ammonium, class preparation can reduce the angiotensin II level and (or) l hyperkalemia and reduce the production of ammonium, will help reduce the renal hypertrophy and avoid excessive ammonium generated by the alternative pathway activation of complement induced tubulointerstitial lesions.
The application of such agents should pay attention to can cause hyperkalemia (especially renal dysfunction), other side effects include rash, itching, fever, flu-like symptoms, diminished sense of taste and rare granulocytes reduce. Some people think that class preparation may cause acute drug-induced interstitial nephritis.
① The expansion of glomerular artery, small arteries of the ball is more significant than the afferent artery dilation, and therefore reduce the pressure inside the ball, reducing renal ball high blood dynamics;
② The angiotensin II-stimulated proximal tubular ammonium, class preparation can reduce the angiotensin II level and (or) l hyperkalemia and reduce the production of ammonium, will help reduce the renal hypertrophy and avoid excessive ammonium generated by the alternative pathway activation of complement induced tubulointerstitial lesions.
The application of such agents should pay attention to can cause hyperkalemia (especially renal dysfunction), other side effects include rash, itching, fever, flu-like symptoms, diminished sense of taste and rare granulocytes reduce. Some people think that class preparation may cause acute drug-induced interstitial nephritis.
Monday, April 9, 2012
Best time of summer, chronic kidney disease treatment
Many kidney specialists pointed out that sick patients with chronic kidney
disease need to raise slowly, but in the period of recuperation, the need to
receive standard treatment, as early as day treatment for kidney protection
significance is not the same, in the summer of kidney patients to ignore is the
treatment chronic nephropathy season.
Why summer is the best season for the treatment of chronic kidney disease? Chinese medicine believes that, especially the dog days of summer, as temperatures rise, the human body yang rising, meridian accessible, with plenty of blood, the resistance is relatively high; the same time, the human body in various tissues and organs function, ability to repair itself in a year the best level. At this point, patients with chronic kidney disease often feel "good", the external symptoms of a variety of kidney disease also are relatively mild. Therefore, some patients are often in the summer of their condition "underestimate the enemy," the idea, they do not rush to be treated in the summer, even mistakenly believe that their own stable condition, and began to recover, the more relaxed the idea of continued treatment. Do you not know that, according to Chinese medicine the dialectical, a lot of chronic kidney disease, chronic nephritis, nephrotic syndrome, all belong to the actual situation mixed, the vacuity of the card. Patients can take advantage of the summer of this favorable opportunity, use of standard means of treatment of certain cold nephropathy, the virtual nephropathy will be able to drive the wind dispelling tonic fitness, to adjust the body's yin and yang balance, a multipliertreatment. This is in fact very simple, as we boil water, under normal circumstances, summer boil a pot of water, certainly better than the winter fast.
Chronic kidney disease, impaired renal intrinsic cells ability to repair itself the highest kidney fibrosis progression is relatively slow. If the patient is able to seize the summer of this favorable opportunity for the treatment of chronic kidney disease, standard treatment of chronic kidney disease, you will be able to receive those who spend less effective, and in stable condition after treatment recurrence.
Therefore, the treatment of chronic kidney disease should seize the favorable opportunity, and early treatment and early rehabilitation. Do not wait until the advent of autumn and winter, the weather cools, human yang latent, relatively low resistance, and again the treatment of chronic kidney disease, when the difficulty of treatment is bound to be greatly enhanced! The reason because of the weather, the patient vulnerable to cold, to the treatment of chronic kidney disease and stable recovery a great deal of variables.
Why summer is the best season for the treatment of chronic kidney disease? Chinese medicine believes that, especially the dog days of summer, as temperatures rise, the human body yang rising, meridian accessible, with plenty of blood, the resistance is relatively high; the same time, the human body in various tissues and organs function, ability to repair itself in a year the best level. At this point, patients with chronic kidney disease often feel "good", the external symptoms of a variety of kidney disease also are relatively mild. Therefore, some patients are often in the summer of their condition "underestimate the enemy," the idea, they do not rush to be treated in the summer, even mistakenly believe that their own stable condition, and began to recover, the more relaxed the idea of continued treatment. Do you not know that, according to Chinese medicine the dialectical, a lot of chronic kidney disease, chronic nephritis, nephrotic syndrome, all belong to the actual situation mixed, the vacuity of the card. Patients can take advantage of the summer of this favorable opportunity, use of standard means of treatment of certain cold nephropathy, the virtual nephropathy will be able to drive the wind dispelling tonic fitness, to adjust the body's yin and yang balance, a multipliertreatment. This is in fact very simple, as we boil water, under normal circumstances, summer boil a pot of water, certainly better than the winter fast.
Chronic kidney disease, impaired renal intrinsic cells ability to repair itself the highest kidney fibrosis progression is relatively slow. If the patient is able to seize the summer of this favorable opportunity for the treatment of chronic kidney disease, standard treatment of chronic kidney disease, you will be able to receive those who spend less effective, and in stable condition after treatment recurrence.
Therefore, the treatment of chronic kidney disease should seize the favorable opportunity, and early treatment and early rehabilitation. Do not wait until the advent of autumn and winter, the weather cools, human yang latent, relatively low resistance, and again the treatment of chronic kidney disease, when the difficulty of treatment is bound to be greatly enhanced! The reason because of the weather, the patient vulnerable to cold, to the treatment of chronic kidney disease and stable recovery a great deal of variables.
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