IgA nephropathy etiology and pathogenesis

The etiology and pathogenesis of IgA nephropathy has not yet been fully understood, is generally believed that IgA nephropathy is a glomerular disease caused by immune complexes. TCM etiology and pathogenesis of IgA nephropathy understanding can be summarized as:
, Pathogenic foreign attacks
Wind clip hot evil foreign attacks, the homes in the lung, downstream bladderwaterways negative, hot forged focus, can cause edema and hematuria.
Second, liver and kidney
Ferrite deficiency, or over-the troubles that liver and kidney yin deficiency, the raw heat,thermal injury Shenluotong hematuria.
Third, spleen and kidney Qi
Ferrite deficiency of qi, or overwork, injuries to the spleen and kidney, resulting inspleen and kidney Qi, Shengqing spleen, kidney failure to seal Tibet, proteinuria, the gas is not taken blood, hematuria.
In short, of IgA nephropathy total yin or qi deficiency-based wind cold, damp heat,blood stasis as the standard, Yin Chang, chief damp heat, qi deficiency with blood stasis.

Membranous nephropathy etiology

The exact cause of this disease is not yet clear, Clinical according to their causes can be divided into primary MN and secondary MN two categories. The former is of unknown etiology, the latter because it often accompanied by autoimmune diseases such as systemic lupus erythematosus, the incidence of hepatitis B and C, is now generally believed that the disease exist autoimmune abnormalities. Secondary causes of membranous nephropathy caused by:
An autoimmune disease systemic lupus erythematosus, rheumatoid arthritis, diabetes, Hashimoto's thyroiditis, Graves disease, mixed connective tissue disease, Sjogren syndrome, primary biliary cirrhosis, ankylosing spondylitis and acute infectious polyneuritis.
(2) infected with hepatitis B, hepatitis C, syphilis, leprosy, filariasis, schistosomiasis and malaria.
Drugs and toxic organic gold, mercury, D-penicillamine, captopril and probenecid.
Tumors of lung cancer, colon cancer, breast cancer and lymphoma.
Sarcoidosis, graft recurrence of sickle cell disease and angiolymphoid hyperplasia (Kimura disease). 75% of membranous nephropathy can not find the above reasons, that is, belonging to idiopathic membranous nephropathy.