Membranous nephropathy etiology

The exact cause of this disease is not yet clear, Clinical according to their causes can be divided into primary MN and secondary MN two categories. The former is of unknown etiology, the latter because it often accompanied by autoimmune diseases such as systemic lupus erythematosus, the incidence of hepatitis B and C, is now generally believed that the disease exist autoimmune abnormalities. Secondary causes of membranous nephropathy caused by:
An autoimmune disease systemic lupus erythematosus, rheumatoid arthritis, diabetes, Hashimoto's thyroiditis, Graves disease, mixed connective tissue disease, Sjogren syndrome, primary biliary cirrhosis, ankylosing spondylitis and acute infectious polyneuritis.
(2) infected with hepatitis B, hepatitis C, syphilis, leprosy, filariasis, schistosomiasis and malaria.
Drugs and toxic organic gold, mercury, D-penicillamine, captopril and probenecid.
Tumors of lung cancer, colon cancer, breast cancer and lymphoma.
Sarcoidosis, graft recurrence of sickle cell disease and angiolymphoid hyperplasia (Kimura disease). 75% of membranous nephropathy can not find the above reasons, that is, belonging to idiopathic membranous nephropathy.