1, systemic manifestations
Systemic manifestations of lupus nephritis with fever, arthritis and skin and
mucous membrane damage is the most common. The system is accompanied by
involvement of the liver, heart, central nervous system and blood-forming
organs, more than 1/3 of patients with polyserositis (pleural and pericardial).
Pulmonary hemorrhage may also be the main one of the manifestations of the
disease, with Goodpasture's disease and small vessel vasculitis differentiated,
Renault sign found in 40% of patients.
2, the renal manifestations
The ① subclinical or "silent" type: kidney involvement, performance, urine
negative, but the pathology is often varying degrees of disease.
② Light: 30% to 50% without clinical symptoms, the only light to moderate
proteinuria (
③ nephrotic syndrome: about 40% to 60%, showed massive proteinuria,
hypoalbuminemia and edema, occasional elevated blood cholesterol, diseases, late
hypertension, renal dysfunction, the majority of patients to renal failure.
④ chronic nephritis: about 35% to 50%, hypertension and varying degrees of
proteinuria, urinary sediment, a large number of red blood cells and casts, and
more with impaired renal function.
The ⑤ acute nephritis: the performance of the clinical manifestations of
acute nephritis.
⑥ rapidly progressive nephritis oliguric acute renal failure, or light or by
the nephrotic syndrome; in a short period of time
Transformed from Pathology showed crescentic glomerulonephritis
⑦ tubule interstitial damage; clinical manifestations of renal tubular
acidosis, nocturia, increased blood pressure, increased urine β2-microglobulin,
half of the patients with renal dysfunction.
⑧ of antiphospholipid antibodies: antiphospholipid antibody positive, major
clinical manifestations of large and small arterial and venous thrombosis and
embolism, platelet reduction and tendency to abortion.
To ⑨ acute renal failure type; oliguric acute renal failure and pathologic
findings for acute tubular necrosis in a short period of time
⑩ chronic renal failure, type: varying degrees of proteinuria, hematuria, and
edema, impaired renal function.
In summary, the above is about the performance of lupus nephritis? Allows
people to timely diagnosis of lupus nephritis, lupus nephritis patients but also
timely symptomatic treatment, eat more fruits and vegetables.