How serious is the nephrotic syndrome?

How serious is the nephrotic syndrome?Many patients are very concerned about the treatment of nephrotic syndrome, the patients in order to a good understanding of nephrotic syndrome is necessary. So, nephrotic syndrome is serious, and made to explain to everyone, I hope we can help.
First we explain the disease complications of nephrotic syndrome
First, due to the large number of immunoglobulin is lost in urine, plasma protein reduced impact of antibody formation. Application of adrenal corticosteroids and cytotoxic compounds, in which patients body defenses are weakened and prone to infection, such as skin infections, primary peritonitis, respiratory tract infections, urinary tract infection, and even induce sepsis.
Second, patients with nephrotic syndrome often have hyperlipidemia, and hypercoagulable states, and therefore prone to coronary heart disease. Coronary heart disease has become a cause of death of nephrotic syndrome factors (after infection and renal failure).
Third, the complications of nephrotic syndrome What are prone to thrombosis in patients with nephrotic syndrome, especially Membranous glomerulonephritis the incidence of up to 25% to 40%.
Fourth, patients with nephrotic syndrome due to massive proteinuria, hypoalbuminemia, hyperlipidemia, often in the low blood volume and a hypercoagulable state in vivo, vomiting, diarrhea, use of antihypertensive drugs and diuretics diuretic can make a sudden decrease in renal blood perfusion, and thus reduce the glomerular filtration rate, leading to acute renal failure.
Disease complications of nephrotic syndrome, we all understand it, if you do not have good control of the disease, disease progression, this is likely to develop into uremia, so patients must be very good control of the disease.