Monday, March 19, 2012

Prognosis of Henoch-Schonlein purpura nephritis

Most purpura nephritis (HSPN) is a good prognosis, the majority can be cured. HSPN ofthe degree of kidney damage with light weight, experience has shown that the prognosisof this disease depends on several factors:
The first is age: Children purpura nephritis patients with good prognosis, very few diedof rapidly progressive glomerulonephritis in the acute phase, the development of end-stage renal disease by 2% to 15%, the development of end-stage kidney donors oftenacute of delayed healing, a history of slow progress; relatively poor prognosis of adult-onset purpura nephritis.
Clinical manifestations: poor prognosis of patients with purpura nephritis massive proteinuria and severe hypertension; is not significant by conventional treatment, earlyrenal damage.
Pathological changes: renal pathological changes in the heavier patients, the greater thelikelihood of progression to chronic renal insufficiency.
It is noteworthy that some children with acute renal involvement is not obvious or hadurine has been normal, but the later occurrence of hypertension, renal dysfunction, thegirls there are adult patients with hypertension and proteinuria after pregnancy easy.Children with allergic purpura urine should be regularly reviewed.

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