Monday, July 30, 2012

The Prognosis of Focal Segmental Glomerulonephritis (FSGS)


Also the use of ACEI to reduce the glomerular pressure, so that proteinuria decreased, but the patients with histological changes did not improve. Therefore, FSGS patients with morphologic changes and functional changes are often inconsistent.

Schulman and other prognosis observed two groups of FSGS in children and found that the clinical and morphological parameters by the following poor prognosis.

As we all know, renal biopsy can be more correctly guess the prognosis of patients. Pathologists often find considerable tissue damage function parameters to speculate on the prognosis. Proteinuria is usually first consider the clinical indicators, however, proteinuria in FSGS patients to remind not seem to meet the prognosis of benign and malignant. It was found that the MCD in patients with massive proteinuria, glomerular no sclerosing lesions to the contrary, when the FSGS patients with proteinuria reduction, it may indicate the increase in the number of FSGS lesions involving the glomerulus; also the use of ACEI to reduce the glomerular pressure, decreased proteinuria, but in patients with histological changes has not improved. Therefore, FSGS patients with morphologic changes and functional changes are often inconsistent.

The main reason for this function is out of line and shape including:

① The lesion of focal and segmental distribution.

② sclerotic glomeruli transitional compensatory.

③ nephron number is reduced.

④ renal blood flow abnormalities.

⑤ plasma colloid osmotic pressure changes.

⑥ changes in glomerular pressure.

FSGS can be Efficiently Treated by Micro-Chinese Medicine Osmotherapy

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